DATABASES ON MEDICINE AND MOLECULAR BIOLOGY
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Atlas of Genetics"  info
 

The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a peer reviewed on-line journal and database in free access on internet devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases.
http://atlasgeneticsoncology.org/

BCCA - Chemotherapy Protocols
 

Chemotherapy protocols, provided by the British Columbia Cancer Agency (BCCA).
http://www.bccancer.bc.ca/HPI/ChemotherapyProtocols/default.htm

BCCA - Drug Index
 

Manual of Chemotherapeutics, provided by the British Columbia Cancer Agency (BCCA).
http://www.bccancer.bc.ca/HPI/DrugDatabase/DrugIndexPro/default.htm

British Committee for Standards in Haematology (BCSH) - Guidelines
 

Guidelines on hematology
http://www.bcshguidelines.com

Complementary and Alternative Medicine (NCI)
 

Scientific evaluation of complementary and alternative medicine by the National Cancer Institute.
http://www.cancer.gov/cancertopics/cam

CAM-Cancer
 

Reliable information on complementary and alternative medicines relating to cancer provided by the European Union (EU).
http://www.cam-cancer.org/

Cancer Chromosomes"  info
 

Three databases, the NCI/NCBI SKY/M-FISH & CGH Database, the NCI Mitelman Database of Chromosome Aberrations in Cancer, and the NCI Recurrent Aberrations in Cancer, are now integrated into NCBI's Entrez system as Cancer Chromosomes.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=Home&DB=cancerchromosomes

Cancer Immunome Database
 

Database about the human immune response to cancer.
http://www2.licr.org/CancerImmunomeDB/

Cancer Registries
 

This website provides access to information on the occurrence of cancer world-wide held by the Unit of Descriptive Epidemiology at the International Agency for Research on Cancer.
http://www-dep.iarc.fr

Cancer Statistics, 2016"  info
 

Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival rates based on incidence data from the National Cancer Institute and mortality data from the National Center for Health Statistics.
http://onlinelibrary.wiley.com/doi/10.3322/caac.21332/epdf

13th Report on Carcinogens
 

The 13th Report on Carcinogens is producec by
U.S. Department of Health and Human Services, Public Health Service,
National Toxicology Program

http://ntp.niehs.nih.gov/pubhealth/roc/roc13/index.html

Chemical Carcinogenesis Research Information System
 

Chemical Carcinogenesis Research Information System - carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition data provided by the National Cancer Institute (NCI).
http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS

Clinical Trials Listing Service
 

Information about more than 41,000 active industry and government-sponsored clinical trials, as well as new drug therapies in research and those recently approved by the FDA.
http://www.centerwatch.com/

Cancer Genome Anatomy Project
 

The Cancer Genome Anatomy Project (CGAP) is an interdisciplinary program established and administered by the National Cancer Institute (NCI) to generate the information and technological tools needed to decipher the molecular anatomy of the cancer cell.
http://www.ncbi.nlm.nih.gov/CGAP/

Catalogue Of Somatic Mutations In Cancer"  info
 

COSMIC (Catalogue of Somatic Mutations in Cancer; http://www.sanger.ac.uk/cosmic) is a comprehensive resource that aims to curate the world's literature on somatic mutations in known cancer genes. The catalog includes full and up-to-date curation of mutation data in over 60 well known point-mutated genes, together with novel gene fusion products expressed across genome rearrangement breakpoints, and all of the somatic mutation data from candidate gene screens at the UK's Cancer Genome Project.
http://www.sanger.ac.uk/cosmic

The Carcinogenic Potency Database"  info
 

The CPDB is a standardized resource on chronic, long-term animal cancer tests. CPDB provides ...
- Quick access to results on 1451 chemicals
- Analyses of experimental design for each of 6008 experiments, including species, strain, dose and protocol
-Analyses of tumor incidence at each target site, dose-response curve shape, carcinogenic potency and statistical significance
http://potency.berkeley.edu/cpdb.html

Differentially Expressed Proteins in Human Cancer Database
 

dbDEPC (database of Differentially Expressed Proteins in Human Cancer) is designed to store and display differentially expressed proteins (DEPs) in human cancers detected by mass spectrometry (MS) approach.
http://protchem.hunnu.edu.cn/depd/

Database of MHC Ligands"  info
 

EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens.
http://bio.dfci.harvard.edu/epimhc/

ESMO Guidelines
 

The ESMO Clinical Recommendations (CR) are clinical guidelines intended to provide the user with a set of requirements for a basic standard of cancer care. Each CR offers vital, evidence-based information for physicians, including the incidence of the malignancy, diagnostic criteria, staging of disease and risk assessment, treatment plans and follow-up.
http://www.esmo.org/education/esmo-clinical-practice-guidelines.html

Gene Therapy Clinical Trials Worldwide
 

Overview about clinical trials on the field of gene therapy, provided by the Journal of Gene Medicine.
http://www.wiley.co.uk/genmed/clinical/

German Cancer Trials
 

Registry of cancer trials in Germany.
http://www.studien.de/

Human Endogenous Retrovirus Database"  info
 

Retroviral genomes or parts of their genomes are present in the DNA of many organisms. Studies of endogenous retroviral nucleotide sequences have become an important part of contemporary retrovirology as well as of molecular and cellular biology and genomics. Human endogenous retroviruses (HERVs) are of special interest also because their expression may be associated with several diseases, including cancer. Various groups of HERVs have been reported in the human genome. Their number can range from one copy to many thousand copies.
http://herv.img.cas.cz

International Cancer Research Portfolio (ICRP)
 

The International Cancer Research Portfolio, or ICRP, represents a database of information on cancer research awards of the cancer funding organizations that comprise the International Cancer Research (ICR) Partners.
http://www.cancerportfolio.com/

Integrated Risk Information System"  info
 

Integrated Risk Information System - data from the EPA in support of human health risk assessment, focusing on hazard identification and dose-response assessment.
http://www.epa.gov/iris/

Database of Human DNA Methylation and Cancer"  info
 

To study interplay of DNA methylation, gene expression and cancer, a database for human DNA Methylation and Cancer was developed. MethyCancer hosts both highly integrated data of DNA methylation, cancer-related gene, mutation and cancer information from public resources, and the CpG Island (CGI) clones derived from our large-scale sequencing. Interconnections between different data types were analyzed and presented. Furthermore, a powerful search tool is developed to provide user-friendly access to all the data and data connections. A graphical MethyView shows DNA methylation in context of genomics and genetics data facilitating the research in cancer to understand genetic and epigenetic mechanisms that make dramatic changes in gene expression of tumor cells.
http://methycancer.psych.ac.cn/

Mouse Models of Human Cancers Consortium Mouse Repository
 

A mouse repository/distribution resource at the NCI-Frederick Cancer Research Center that:

  • Supplies mouse cancer models and associated strains and information pertaining to them to the scientific community
  • Accepts mouse models and suggestions of models for inclusion in the Repository from members of the scientific community
  • Maintains cryopreserved stocks of mouse models and associated strains
    http://mouse.ncifcrf.gov/

  • Mouse Tumor Biology Database
     

    The Mouse Tumor Biology (MTB) Database supports the use of the mouse as a model system of hereditary cancer by providing electronic access to:
    Descriptions of tumors (data are organized by strain and organ of tumor origin),
    Tumor frequency and latency data,
    Information on genetic factors associated with tumors and tumor development,
    Tumor pathology reports and images,
    References, both published and unpublished, and
    Links to related online resources including:
    http://tumor.informatics.jax.org/FMPro?-db=TumorInstance&-format=mtdp.html&-view

    Myc Cancer Gene"  info
     

    Diese Website enthält Links zu folgenden Datenbanken:

  • Myc Target Gene Database
  • Myc and Human Cancer Database
  • Myc Protein - Protein Interaction Database
    http://www.myc-cancer-gene.org/

  • National Comprehensive Cancer Network
     

    The most famous U.S. cancer centers are affiliated into the National Comprehensive Cancer Network (NCCN). Members are e.g. the Fred Hutchinson Cancer Research Center, the Memorial Sloan-Kettering Cancer Center, the Dana-Farber Cancer Care Center, the M.D. Anderson Cancer Center as well as the City of Hope Cancer Center.
    This Site provides carefully compiled guidlines for the diagnosis and treatment of cancer.
    http://www.nccn.org/

    NCI Investigational Drugs Data
     

    A database about investigational drugs, provided by the NCI.
    http://dtp.nci.nih.gov/docs/idrugs/chemdata.html

    Directory of Research Tools and Services for Cancer Researchers
     

    Research Tools and Services, provided by the NCI, National Cancer Institute.
    http://resresources.nci.nih.gov/

    NCI: Clinical Trials
     

    Clinical trials by the Natioanl Cancer Instiute (NCI).
    http://cancer.gov/search/clinical_trials/search_clinicaltrialsadvanced.aspx

    Nuclear Matrix Associated Proteins - Database"  info
     

    NMP-db is a database of nuclear matrix associated proteins, produced by Sven Mika @ Rost Group, Columbia University, New York.
    http://www.rostlab.org/services/NMPdb/

    OncoLink - Clinical Trials
     

    This excellent website, made by the Abramson Cancer Center of the University of Pennsylvania, provides a database of clinical cancer trials.
    http://www.oncolink.com/treatment/trials.html

    OncologySTAT
     

    Oncology informations produced by Elsevier. About 240 Chemothrapy Regimens are provided.
    http://www.oncologystat.com/

    Cancer Microarray Database - Oncomine
     

    ONCOMINE collects all publicly available cancer microarray studies.
    https://www.oncomine.org/

    Physician Data Query
     

    PDQ (Physician Data Query) is NCI's comprehensive cancer database. It contains peer-reviewed summaries on cancer treatment, screening, prevention, genetics, and supportive care; a registry of approximately 1,800 open and 12,000 closed cancer clinical trials from around the world; and directories of physicians, professionals who provide genetics services, and organizations that provide cancer care.
    http://cancer.gov/cancerinfo/pdq/adulttreatment

    Physician Data Query
     

    PDQ (Physician Data Query) is NCI's comprehensive cancer database. It contains peer-reviewed summaries on cancer treatment, screening, prevention, genetics, and supportive care; a registry of approximately 1,800 open and 12,000 closed cancer clinical trials from around the world; and directories of physicians, professionals who provide genetics services, and organizations that provide cancer care.
    http://cancer.gov/cancerinfo/pdq/adulttreatment

    PDQ - Clinical Trials
     

    Clinical Trials on the field of oncology.
    http://www.cancer.gov/clinicaltrials/

    Recurrent Chromosome Aberrations in Cancer
     

    The recurrent aberrations were derived from the Mitelman Database of Chromosome Aberrations in Cancer (2003) and include all cytogenetic changes present in at least two cases of the same morphologic entity, and, whenever applicable for solid tumors, within the same site. The complete karyotypes, patient characteristics, and references are found in the Mitelman Database of Chromosome Aberrations in Cancer.
    http://cgap.nci.nih.gov/Chromosomes/RecurrentAberrations

    Surveillance, Epidemiology and End Results"  info
     

    Epidemiologic database by the NCI, USA.
    http://seer.cancer.gov/

    Spectral Karyotyping (SKY) / Comparative Genomic Hybidization (CGH)"  info
     

    Spectral Karyotyping (SKY) and Comparative Genomic Hybidization (CGH) are complementary fluorescent molecular cytogenetic techniques that have revolutionized the detection of chromosomal abnormalities. SKY permits the simultaneous visualization of all human or mouse chromosomes in a different color, facilitating the detection of chromosomal translocations and rearrangements. CGH uses the hybridization of differentially labeled tumor and reference DNA to generate a map of DNA copy number changes in tumor genomes.
    http://www.ncbi.nlm.nih.gov/sky/

    The Cancer Genome Atlas
     

    The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing. TCGA is a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI), which are both part of the National Institutes of Health, U.S. Department of Health and Human Services.
    http://cancergenome.nih.gov/

    Common Terminology Criteria for Adverse Events (CTCAE) / National Cancer Institute
     

    Toxicity criteria of the NCI.
    http://www.fda.gov/cder/cancer/toxicityframe.htm

    IARC TP53 Mutation Database"  info
     

    In 1991, a database of TP53 somatic mutations in human cancers and cell-lines was initiated by Monica Hollstein and Curtis Harris. Since 1994, this database has been maintained at the International Agency for Research on Cancer (IARC) in Lyon, France and is made freely available as a service to the scientific community.
    The IARC TP53 Mutation Database is now maintained by the Unit of Molecular Carcinogenesis (MOC) at IARC, under the supervision of Pierre Hainaut.
    The project consists of three aspects:
    Perform regular review of the TP53 mutation literature
    Develop electronic formats for compiling, sorting and retrieving mutation data
    Perform research on TP53 mutation patterns
    http://www-p53.iarc.fr/

    Treatment Protocols / Cancer Care Ontario
     

    Chemotherapy protocols, provided by Cancer Care Ontario.
    http://www.cancercare.on.ca/cms/One.aspx?portalId=1377&pageId=11128

    Tubafrost
     

    Tubafrost is the central European database collecting the information of frozen tumor tissue specimens.
    http://www.tubafrost.org/

    The Wnt gene Homepage
     

    Wnt proteins form a family of highly conserved secreted signaling molecules that regulate cell-to-cell interactions during embryogenesis. Wnt genes and Wnt signaling are also implicated in cancer. Insights into the mechanisms of Wnt action have emerged from several systems: genetics in Drosophila and Caenorhabditis elegans; biochemistry in cell culture and ectopic gene expression in Xenopus embryos. Many Wnt genes in the mouse have been mutated, leading to very specific developmental defects.
    http://www.stanford.edu/group/nusselab/cgi-bin/wnt/