DATABASES ON MEDICINE AND MOLECULAR BIOLOGY
|CpG Island Database|
UHN Microarray Centre's CpG Island Database. Here you will find all the information you need to get started with analysing your results from experiments performed on our HCGI 12K and HCGI 8.1K Microarray chip.
EpiFactors is a database for epigenetic factors, corresponding genes and products. Epigenetic factors are defined as:
Proteins that change the general structure of chromatin (chromatin remodeling), including
Proteins that act upon post-translational modifications of histones (histone modification read, write and erase);
Proteins that move, eject or restructure nucleosomes (ATP-dependent chromatin remodelers);
Proteins that incorporate histone variants into the nucleosomes.
Specific subgroups of proteins may be annotated as such, e.g. the Polycomb group (PcG) proteins.
Protein cofactors forming complexes with epigenetic factors, where complex formation is important for the activity (cofactor).
Proteins acting as histones, histone variants or protamines (histone).
Proteins assisting histone folding and assembly (histone chaperone).
Proteins that act upon modifications of DNA or RNA in such a way that it affects gene expression, but not throught RNA precessing (DNA or RNA modification).
|Epigenetics Product Database|
Database about laboratory products used in the epigenetic research field.
|Database for DNA Methylation and Environmental Epigenetic Effects" info|
The purpose of this database is to provide the scientific community with a resource to store DNA methylation data and to make these data readily available to the public. Futur development of the database will focus on environmental effects on DNA methylation. It attempts to store all data about DNA methylation in a common source. It can be searched in different ways, ranging from a simple browse mode to detailed queries for sequence-specific DNA methylation profiles and patterns, total methylation content data or environmental conditions that can influence the methylation state of DNA.
|Prostate Epigenetic Database|
Prostate cancer (PC) develops in the prostate (a male sex gland) and is a common malignancy and a leading cause of cancer death among men. In addition to genetic alteration, epigenetic aberration plays key roles in progression of PC. Studies in epigenetic changes in PC have accumulated vast amount of useful data that could shed light on the development of PC and include potential epigenetic markers as diagnosis and prognosis for PC. Therefore, we constructed PEpiD to store the curated epigenetic data retrieved by literature mining, which previous studies indicated as involved in PC of human, mouse, and rat. A user-friendly interface is implemented for easy and flexible query. PEpiD can serve as an important resource for epigenetic research in PC.
|The Restriction Enzyme Database" info|
A collection of information about restriction enzymes and related proteins. It contains published and unpublished references, recognition and cleavage sites, isoschizomers, commercial availability, methylation sensitivity, crystal and sequence data. DNA methyltransferases, homing endonucleases, nicking enzymes, specificity subunits and control proteins are also included. Putative DNA methyltransferases and restriction enzymes, as predicted from analysis of genomic sequences, are also listed. REBASE is updated daily and is constantly expanding. REBASE was made by
Nobel laureate Dr. Richard J. Roberts and Dana Macelis.