DATABASES ON MEDICINE AND MOLECULAR BIOLOGY
|Short Tandem Repeat DNA|
While the use of STRs for genetic mapping and identity testing has become widespread among DNA typing laboratories, there is no single place where information may be found regarding STR systems. This web site is an attempt to bring together the abundant literature on the subject in a cohesive fashion to make future work in this field easier. Facts and sequence information on each STR system, population data, commonly used multiplex STR systems, PCR primers and conditions, and a review of various technologies for analysis of STR alleles have been included in this database. Addresses for scientists and organizations working in this area have also been included as well as a comprehensive reference listing of material on STRs used for DNA typing purposes.
|The Y-Chromosome Haplotype Reference Database" info|
The ability to identify male-specific DNA renders polymorphic Y-chromosomal sequences an invaluable addition to the standard panel of autosomal loci used in forensic genetics (Roewer 2009). Y-STR haplotyping is particularly important for sensitive typing of male DNA in mixed stains as well as for rapid assortment of biological crime scene evidence. Moreover, Y chromosomal profiling can trace back paternal lineages into the past and has thus been proven a useful tool in genealogical and kinship testing. The individuality of the male-specific part of the Y chromosome can be optimally explored by the Y-STR haplotype analysis using a set of highly variable short tandem repeat markers approved by the forensic and scientific community.