DATABASES ON MEDICINE AND MOLECULAR BIOLOGY
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American Type Culture Collection
 

ATCC is a global nonprofit bioresource center that provides biological products, technical services, and educational programs to private industry, government, and academic organizations around the world. Our mission is to acquire, authenticate, preserve, develop, and distribute biological materials, information, technology, intellectual property, and standards for the advancement, validation, and application of scientific knowledge.
http://www.atcc.org/

Registry of Standard Biological Parts
 

The Registry is a collection of genetic parts that can be mixed and matched to build synthetic biology devices and systems. Founded in 2003 at MIT, the Registry is part of the Synthetic Biology community's efforts to make biology easier to engineer. It provides a resource of available genetic parts to iGEM teams and academic labs.
http://biobricks.org/

Biochemical Nomenclature Committees
 

Nomenklatur by the International Union of Pure and Applied Chemistry and by the International Union of Biochemistry and Molecular Biology.

http://www.chem.qmul.ac.uk/iupac/jcbn/

Blood Group Antigen Gene Mutation Database
 

The database is constructed under the aegis of the Human Genome Variation Society (HGVS); it is a Locus Specific Database (LSDB).. It deals with mutations in loci of allelic genes that specify the antigens of 28 blood group systems (includes all those for which the molecular basis is defined ) and the allelic variants of those genes. Orthologues of a number of genes are included.
The database is compiled and curated by Olga O. Blumenfeld, Department of Biochemistry and constructed by Santosh Patnaik, Department of Cell Biology, Albert Einstein College of Medicine, New York, NY. Collaborators include Marion E. Reid, Laboratory of Immunochemistry, and Cheng-Han Huang, Laboratory of Biochemistry and Molecular Genetics, New York Blood Center, New York, NY.
http://www.bioc.aecom.yu.edu/bgmut/index.htm

The University of Michigan Human Breast Cancer Cell Lines
 

Stephen P. Ethier, Ph.D Department of Radiation Oncology, The University of Michigan Medical School, and Breast Oncology Program, The University of Michigan Comprehensive Cancer Center, 1500 E. Medical Center Dr., Ann Arbor, MI 48109-0984.
In 1995 The University of Michigan Breast Cell/Tissue Bank and Data Base came into existence as a result of an infrastructure grant awarded to the U of M by the Department of Defense. This resource had been developed internally over the previous six years as a result of the Principal Investigators interest in breast cancer biology and because of the need to carry out breast cancer biology studies using freshly isolated human breast cancer cells. The need for new human breast cancer cell lines that can be cultured under defined conditions in vitro also contributed to the motivation to develop this resource.
http://www.cancer.med.umich.edu/breast_cell/Production/index.html

CD - Nomenclature
 

Nomenclature proposed in 1982 at First International Workshop and Conference on Human Leukocyte Differentiation Antigens (HLDA); workshops now called Human Cell Differentiation Molecules.
http://www.pathologyoutlines.com/cdmarkers.html

Chemcyclopedia
 

Chemcyclopedia’s encyclopedic coverage of the world’s major chemical products embraces the following principal areas:

  • Organic (aliphatic, aromatic, alicyclic, heterocyclic, hydrocarbon, chiral)
  • Organometallic
  • Inorganic (metallic, non-metallic, rare-earth)
    with many hundreds of Specialty and Fine Chemicals being represented.
    http://www.chemcyc.org/

  • Chemfinder
     

    CHEMFINDER finds ...
    Chemical Structures: 2D structures & 3D models
    Physical Properties: MP, BP, CAS RN, & more
    Hyperlinks: Links to other websites with information about the searched compound
    http://www.chemfinder.com

    Clotting factor concentrates
     

    Information about clotting factor concentrates, provided by the International Society on Thrombosis and Haemostasis.
    http://www.isth.org/LinkClick.aspx?fileticket=XajEnCuUBEg%3d&tabid=81

    Vitamin-K dependant Serine Protease Mutation Database
     

    Information on coagulation point mutations together with structural analysis of the domain structures within coagulation proteases. At the moment, the database holds mutations within the five vitamin-K dependant proteases, Thrombin (also known as Factor II), Factor VII (FVII), Factor IX (FIX), Factor X (FX) and Protein C.
    http://www.coagmdb.org/

    Cytokines Online Pathfinder Encyclopaedia (cope)
     

    Encyclopaedia of cytokines.
    http://www.copewithcytokines.de/cope.cgi

    Coriell Cell Repositories
     

    The CORIELL CELL REPOSITORIES provide essential research reagents to the scientific community by establishing, verifying, maintaining, and distributing cells cultures and DNA derived from cell cultures.
    http://ccr.coriell.org/

    Central Research Infrastructure for molecular Pathology
     

    CRIP provides anonymized data on and from human biospecimen available for basic, preclinical and clinical research projects in its database partners’ institutes. Web-based query requires prior user’s registration and is for free for researchers both from academia and industry. CRIP covers data from all disease areas for R&D in molecular and clinical medicine.
    http://www.crip.fraunhofer.de/

    German Collection of Cell Cultures
     

    The DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (German Collection of Microorganisms and Cell Cultures) is an independent, non-profit organization dedicated to the acquisition, characterization, preservation and distribution of bacteria, cell lines, fungi, phages, plasmids, plant cell cultures, plant viruses and yeasts. Established in 1969 in Göttingen the DSM originally belonged to the Gesellschaft für Strahlenforschung (GSF, München), but was later moved to Braunschweig to become a department within the Gesellschaft für Biotechnologische Forschung (GBF). In 1987 the DSM was reorganized as an independent institute in the form of a GmbH (Ltd.) that is owned by the State of Lower Saxony. In 1996, after becoming an "Institut der blauen Liste" (now designated "Wissenschaftsgemeinschaft Gottfried Wilhelm Leibnitz"), the abbreviation of the name of the institute was changed to DSMZ, thus acknowledging the growing importance of the cell culture department.
    http://www.dsmz.de/

    European Collection of Cell Cultures
     

    The European Collection of Cell Cultures (ECACC), established in 1984, is a provider of high quality cell cultures and associated services to industry and the academic research community.
    ECACC is a strategic business unit within the Centre for Applied Microbiology and Research (CAMR), a centre of excellence employing more than 300 scientists and internationally renowned for its work on infectious diseases: their diagnosis, transmission, pathology, prevention and cure. In more recent years CAMR has enhanced its reputation for vaccine development and pilot scale manufacturing development and is increasingly active in the areas of biopharmaceuticals and biosafety. Consequently, ECACC's business is supported by a unique depth and diversity of scientific expertise.
    http://ecacc.org.uk/

    Epigenetics Product Database
     

    Database about laboratory products used in the epigenetic research field.
    http://www.epigenie.com/Epigenetics-Research-Products.html

    European Searchable Tumour Line Database (ESTDAB) Database and Cell Bank"  info
     

    The European Searchable Tumour line Database (ESTDAB) (http://www.ebi.ac.uk/ipd/estdab) is a freely available and fully searchable database of melanoma-derived cell lines, which have been characterised for over 250 immunologically relevant markers by a consortium of European scientists. The database is linked to a cell bank, which can provide melanoma cell lines to non-profit investigators for a nominal handling charge.
    http://www.ebi.ac.uk/ipd/estdab/

    European Synthetic Biology Projects
     

    Repository of synthetic biology projects supported by the European Commission and others.
    http://www.synbiosafe.eu/index.php?page=other-sb-projects

    Factor XI Deficiency Mutation Database"  info
     

    This is a database of mutations within the coagulation Factor XI (FXI) that cause FXI deficiency.
    http://www.factorxi.org/

    FH aHUS Mutation Database"  info
     

    Atypical hemolytic uremic syndrome (aHUS) is a disease of hemolytic anemia, thrombocytopenia, and renal failure associated with defective alternative pathway (AP) complement control. Here, new aHUS mutations are reported for the complement regulatory proteins Factor H (FH), Factor I (FI), and membrane cofactor protein (MCP). Additional mutations or polymorphisms within CFH have been associated with membranoproliferative glomerulonephritis (MPGN) and age-related macular degeneration (AMD). The database includes substitutions that predispose to aHUS, MPGN, and AMD. For this, structural models for the domains in MCP and FI were developed using homology modeling. Patients with mutations in more than one gene can be displayed and interpreted in a coherent manner. The database also includes SNP polymorphisms in CFH, MCP, and IF.
    http://www.fh-hus.org/

    Fibrinogen Database
     

    Database about dysfibrinogenaemias.
    http://www.geht.org/databaseang/fibrinogen/

    GeneTests"  info
     

    By providing current, authoritative information on genetic testing and its use in diagnosis, management, and genetic counseling, GeneTests promotes the appropriate use of genetic services in patient care and personal decision making.
    http://www.geneclinics.org/

    GENETRAP / IGTC
     

    Gene trapping is a high-throughput approach that is used to introduce insertional mutations across the genome in mouse embryonic stem (ES) cells. In addition to generating standard loss-of-function alleles, newer gene trap vectors offer a variety of post-insertional modification strategies for the generation of other experimental alleles. The International Gene Trap Consortium (IGTC) represents all publicly available gene trap cell lines, which are available on a non-collaborative basis for nominal handling fees. Researchers can search and browse the IGTC database for cell lines of interest using accession numbers or IDs, keywords, sequence data, tissue expression profiles and biological pathways.
    http://www.cmhd.ca/sub/genetrap.asp

    German biobank registry"  info
     

    German biobank registry. As the first level of the German Biobanks Registry a registry with the names, addresses of the contact persons, web links and basic information of the biobanks was installed.
    http://www.biobanken.de/

    Haemophilia B Mutation Database
     

    The Haemophilia B Mutation Database informs about point mutations and short additions and deletions in the factor IX gene.
    http://www.kcl.ac.uk/ip/petergreen/haemBdatabase.html

    Haemophilia A Mutation Database
     

    Haemophilia A Mutation Database is a resource site for work on factor VIII.
    http://europium.csc.mrc.ac.uk/

    European Human Embryonic Stem Cell Registry"  info
     

    The European Human Embryonic Stem Cell Registry (hESCreg) is funded as a Specific Support Action under the ‘Life Sciences, Genomics, and Biotechnology for Human Health’ Priority within the 6th Framework Programme for Research and Technological Development of the European Commission. hESCreg was created to offer the research community, legislators, regulators and the general public at large an in-depth overview on the current status of hESC research in Europe. Its present content is the result of a survey by the project team, its partners and the input from numerous hESC line providers. The database has now entered its first public evaluation stage and will be continually developed. This database of some 650 hESC lines that have been derived in Europe and beyond (as of August 2009) is freely accessible. Providers of hESC lines and researchers who work with these cell lines are invited to register - also free of charge - and provide detailed characteristics on their cell lines or information on their research.
    http://www.hescreg.eu/

    Human Plasma Membrane Receptome
     

    The human plasma membrane receptome is a protein sequences, literature, and expression database.
    http://receptome.stanford.edu/HPMR/

    Cell Line Database
     

    contains detailed information on 4.850 human and animal cell lines that are available in many Italian laboratories and in some of the most important European cell banks and cell culture collections.
    http://bioinformatics.hsanmartino.it/hypercldb/

    Interlab Cell Line Collection
     

    The Interlab Cell Line Collection (ICLC) of the National Institute for cancer Research of Genoa was set up in 1994 and offers a service of storage, quality control and distribution of certified human and animal cell lines.
    http://www.iclc.it/details/mixs_new.php

    ISTH-SSC VWF Online Database
     

    Up-to-date databases of point mutations, insertions, deletions, and polymorphisms found in the gene for human von Willebrand Factor.
    http://www.vwf.group.shef.ac.uk/

    The Merck Chemical Databases
     

    The Merck Online Catalog provides basic informations about chemicals.
    http://www.merck-chemicals.com/germany/all-products

    Model Database
     

    ModelDB provides an accessible location for storing and efficiently retrieving compartmental neuron models. ModelDB is tightly coupled with NeuronDB. Models can be coded in any language for any environment, though ModelDB has been initially constructed for use with NEURON and GENESIS. Model code can be viewed before downloading and browsers can be set to auto-launch the models.
    http://senselab.med.yale.edu/senselab/ModelDB/default.asp

    Neuron Database
     

    NeuronDB provides a dynamically searchable database of three types of neuronal properties: voltage gated conductances, neurotransmitter receptors, and neurotransmitter substances. It contains tools that provide for integration of these properties in a given type of neuron and compartment, and for comparison of properties across different types of neurons and compartments.
    http://senselab.med.yale.edu/neurondb/

    Pathology Outlines
     

    Free, regularly updated surgical pathology outlines with links to journal articles, gross and microscopic images, as well as extensive listings of pathology related jobs, fellowships and conferences.
    http://www.pathologyoutlines.com/

    Prokaryotic Growth Temperature Database"  info
     

    Included in PGTdb (Prokaryotic Growth Temperature database) are a total of 1334 temperatures, from 1072 prokaryotic organisms, Bacteria and Archaea. PGTdb integrates microorganisms' growth temperature data from literature survey with their nucleotide/protein sequence, protein family and structure data from related databases.
    http://pgtdb.csie.ncu.edu.tw/

    Plastics Web / Medical Plastics Search - PROSPECTOR
     

    Prospector is a search engine for technical datasheets that provide design, processing and property information for 80,000 plastic materials from 700 global resin manufacturers.
    http://www.ides.com/

    Plasma Proteome Database
     

    PPD is a comprehensive list of blood proteins from Johns Hopkins University in Baltimore, Maryland, and the Institute of Bioinformatics in Bangalore, India. There is information about data from the literature on the more than 7500 protein variants that enter the plasma at some time. For each version, or isoform, one can find standard genomic information such as gene and amino acid sequences.
    http://www.plasmaproteomedatabase.org/

    HUPO - Plasma Proteom Project"  info
     

    HUPO initiated the Plasma Proteome Project (PPP) in 2002. Its pilot phase has (1) evaluated advantages and limitations of many depletion, fractionation, and MS technology platforms; (2) compared PPP reference specimens of human serum and EDTA, heparin, and citrate-anti-coagulated plasma; and (3) created a publicly-available knowledge base (www.bioinformatics.med.umich.edu/hupo/ppp; www.ebi.ac.uk/pride).
    http://www.bioinformatics.med.umich.edu/hupo/ppp

    Rare Bleeding Disorder Database
     

    Rare bleeding disorders (RBDs) are very rare diseases. Together with von Willebrand disease, a defect of primary hemostasis associated with a secondary defect in coagulation factor VIII (FVIII), these X-linked disorders include 95% to 97% of all the inherited deficiencies of coagulation factors -1-. The other 3-5% are represented by the less common inherited disorders. This include deficiency of fibrinogen, prothrombin, factors V, combined V+VIII, VII, X, XI and XIII. These disorders are inherited in an autosomal recessive manner (Figure 1) and their prevalence is approximately 1:500.000 or less in the general population of western countries (Table 1) -1- However their frequency is increased 10-20 times where consanguineous marriages are practised such as Middle East countries and in Southern India - 2-.
    http://www.rbdd.org/

    Rochester Test Catalog (MAYO Clinic)"  info
     

    Test Catalog by MAYO Medical Laboratories.
    http://www.mayomedicallaboratories.com/test-catalog/diseases/A

    Tubafrost
     

    Tubafrost is the central European database collecting the information of frozen tumor tissue specimens.
    http://www.tubafrost.org/

    Virtual Cell Animation Collection
     

    MOLECULAR AND CELLULAR BIOLOGY LEARNING CENTER The lessons are produced in cooperation between the National Sience Foundation and the U.S. Department of Education.
    http://vcell.ndsu.nodak.edu/animations/

    Voltage-gated Potassium Channel Database"  info
     

    Voltage-gated potassium channel database (VKCDB) is designed to serve as a resource for research on voltage-gated potassium channels. Protein sequences, references, functional data and many other relevant data are included in this database.
    http://vkcdb.biology.ualberta.ca

    The Zebrafish Information Network"  info
     

    ZFIN serves as the zebrafish model organism database.
    http://zfin.org/